Korean J Psychopharmacol.
2006 Sep;17(5):449-455.
Korean Medication Algorithm for Bipolar Disorder 2006(IV): Rapid Cycling
- Affiliations
-
- 1Department of Psychiatry, College of Medicine, Hallym University, Anyang, Korea.
- 2Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. wmbahk@catholic.ac.kr
- 3Department of Psychiatry, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
- 4Naju National Hospital, Naju, Korea.
- 5Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.
- 6Department of Psychiatry and Stress Research Institute, College of Medicine, Inje University, Seoul, Korea.
- 7Department of Psychiatry, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.
- 8Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea.
- 9Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.
- 10Department of Psychiatry, College of Medicine, Konkuk University, Chungju, Korea.
- 11Department of Neuropsychiatry, College of Medicine, Chung-Ang University, Seoul, Korea.
- 12Korean College of Neuropsychopharmacology, Korean Society for Depressive and Bipolar Disorders, and Korean Academy of Schizophrenia, Seoul, Korea.
Abstract
OBJECTIVE
The development of treatment guidelines has emerged as an important element so as to standardize treatment and to provide clinicians with algorithms. From the previous publication of Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP): rapid cycling in 2002, we revised that in 2006.
METHODS
The questionnaire to survey the expert opinion of medication for rapid cycling was completed by the review committee consisting of 53 experienced Korean psychiatrists. It is composed of 7 questions, and each question includes various options. We classified the expert opinion to 3 categories based on the lowest category in which the confidence interval fell (6.5 < or = for first-line and 3.5< or = for second-line treatment).
RESULTS
Generally, 'treatment of choice' for rapid cycling was not demonstrated. The first-line treatment is the combination of a mood stabilizer and an atypical antipsychotic. Combination of two mood stabilizers was preferred as next strategy. Divalproex and lithium were the first-line choice as mood stabilizer. Compared to the surveys in 2002, the preference for lamotrigine and atypical antipsychotics has increased while that of carbamazepine and antidepressant has decreased.
CONCLUSION
With the result of the survey, the discussion in executive committee, and the evidences from clinical studies, we have revised KMAP-BP for rapid cycling.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of Ultra-rapid Cycling Bipolar Disorder Recovered by Lamotrigine Combination
- Korean Medication Algorithm for Bipolar Disorder(IV): Rapid Cycling
- Lurasidone in Therapy of Treatment-resistant Ultra-rapid Cycling Bipolar Disorder: Case Report
- Korean Medication Algorithm for Bipolar Disorder(I)
- Korean Medication Algorithm Project for Bipolar Disorder 2022: Rapid Cycling
