Korean J Psychopharmacol.  1997 Apr;8(1):148-154.

A Case of the Dextromethorphan Hydrobromide Induced Mood Disorder with Manic Features

• Choi MJ
• Min SK

Abstract

The authors report a case of dexfromethorphan induced mood disorder with the review of literafures. The patient is a 19-year old female who had been taking dextromethorphan hydrobromide (trade name : romilar) for 14 month s to enjoy its pleasurable effects and to reduce anxiely. Acute intoxication symptoms of dextromethorphan hydrobromide were silly smiles, a euphoric feeling of floating and an optimistic mood. Tolerance developed and she had been taking 70 tablets (1050mg) ot maximum per day. Withdrawal symptoms were anxiely and its related symptoms and a craving for the drug. While taking 50 tagblets per day about 12 days prior to admission, she had developed leated and irritable mood. grandicstily and auditory hallucinations. These symptoms continued despite discontinuation of the drug after admission. the degree of elated and irritable patient's mood was prominent. flight of ideas was not so severe. However, there was prominent grandiosity and auditory hallucinations. She was treated with haloperidol and lithium and then showed gradual remission in 3weeks. If would necessary to explore any drug abuse history in psychiatric patients who are in their teens.

Keyword

Dextromethorphan; Mood disorder

MeSH Terms

Adolescent
Dextromethorphan*
Female
Hallucinations
Haloperidol
Humans
Irritable Mood
Lithium
Mood Disorders*
Substance Withdrawal Syndrome
Substance-Related Disorders
Tablets
Young Adult
Dextromethorphan
Haloperidol
Lithium
Tablets