Korean J Psychopharmacol.  2001 Sep;12(3):255-259.

Aspiration Pneumonia during Clozapine Therapy

Affiliations
  • 1Department of Neuropsychiatry, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Korea. behav@unitel.co.kr
  • 2Seoul National Mental Hospital, Seoul, Korea.

Abstract

Authors experienced aspiration pneumonia during clozapine therapy in a 31 year-old woman patient with treatment-resistant schizophrenia. Development of aspiration pneumonia appeared to be related with side effects of clozapine including sedation, sialorrhea, and esophageal dysfunction. Each side effect seems to be mild, however it can cause fatal problems such as aspiration pneumonia if they appear simultaneously.

Keyword

Clozapine; Side effect; Aspiration pneumonia; Sialorrhea; Sedation; Esophageal dysfunction

MeSH Terms

Adult
Clozapine*
Female
Humans
Pneumonia, Aspiration*
Schizophrenia
Sialorrhea
Clozapine
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