Infect Chemother.  2004 Jun;36(3):181-184.

A Case of Cerebral Toxoplasmosis in a Patient with Acquired Immune Defeciency Syndrome

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea. mdssampak@yahoo.co.kr
  • 2Department of Pathology, College of Medicine, Pusan National University, Busan, Korea.
  • 3Department of Neurosurgery, College of Medicine, Pusan National University, Busan, Korea.
  • 4Department of Diagnostic Radiology, College of Medicine, Pusan National University, Busan, Korea.

Abstract

Toxoplasmosis is one of the most common opportunistic infection of the central nervous system in patients with acquired immunodeficiency syndrome(AIDS). There have been few reports of cerebral toxoplasmosis in patients with AIDS in Korea. In most cases, the diagnosis was assisted by serology and neuroradiologic findings. Making a reliable diagnosis of acute cerebral toxoplasmosis is difficult in patients with AIDS because of the lack of specificity of serologic data and neuroradiological findings. We report a case of 32-year-old man who presented with decreased mentality and fever. Brain MRI showed multiple ill-defined mass-like lesions in both basal ganglia and right thalamus. Stereotatic brain biopsy revealed small parasitic cysts which were filled with toxoplasmic bradyzoites in inflammatory brain tissue.

Keyword

Cerebral toxoplasmosis; AIDS

MeSH Terms

Adult
Basal Ganglia
Biopsy
Brain
Central Nervous System
Diagnosis
Fever
Humans
Korea
Magnetic Resonance Imaging
Opportunistic Infections
Sensitivity and Specificity
Thalamus
Toxoplasmosis
Toxoplasmosis, Cerebral*
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