Infect Chemother.
2005 Feb;37(1):47-49.
An Outbreak of Acute Febrile Reaction Developed after the Administration of Teicoplanin
- Affiliations
-
- 1Division of Infectious Diseases, Sanggyepaik Hospital, College of Medicine, Inje University, Seoul, Korea. kimbn@sanggyepaik.ac.kr
- 2Division of Pharmacy, Sanggyepaik Hospital, College of Medicine, Inje University, Seoul, Korea.
Abstract
- An outbreak of acute febrile reaction which developed after the administration of teicoplanin was identified in seven patients. Fever, with hypotension in some, developed during or soon after infusion and persisted for several hours. Laboratory abnormalities including leukocytosis and elevation of liver enzymes and creatine phosphokinase in serum were observed for two or three days. Contamination of the drug with endotoxins was identified.
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