Korean J Pediatr.  2013 Jul;56(7):304-307. 10.3345/kjp.2013.56.7.304.

Polyclonal gammopathy related to renal bleeding in a peritoneal dialysis patient

Affiliations
  • 1Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Korea. chomh@knu.ac.kr

Abstract

Polyclonal gammopathy represents the diffuse activation of B cells and is usually related to inflammation or immune-related diseases. However, the mechanisms leading to polyclonal gammopathy are essentially speculative. Generally, infectious, inflammatory, or various other reactive processes may be indicated by the presence of a broad-based peak or band in the gamma region on serum protein electrophoresis results. A 15-year-old girl, who had been receiving peritoneal dialysis, presented with polyclonal gammopathy and massive gross hematuria. Renal artery embolization was performed, after which the continuous bleeding subsided and albumin-globulin dissociation resolved. This is a rare case of polyclonal gammopathy related to renal bleeding.

Keyword

Child; Polyclonal gammopathy; Renal bleeding

MeSH Terms

B-Lymphocytes
Child
Dissociative Disorders
Electrophoresis
Hematuria
Hemorrhage
Humans
Inflammation
Peritoneal Dialysis
Renal Artery
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