Gut Liver.  2009 Sep;3(3):215-217.

Simultaneous Colonic Obstruction and Hydroureteronephrosis due to Mesenteric Fibromatosis

• Jung SH
• Paik CN
• Jung JH
• Lee KM
• Chung WC
• Yang JM

Abstract

Mesenteric fibromatosis (MF) is a rare benign mesenchymal lesion that can occur throughout the gastrointestinal tract, especially small bowel. Its biological behavior is intermediate between benign fibrous tissue proliferation and malignant fibrosarcoma. In previously reported cases of MF, we could find colonic obstruction or ureter obstruction, but simultaneous involvement of colon and ureter was not able to be seen. We described a patient that presented with colonic obstruction and hydroureteronephrosis due to MF at sigmoid colon which mimicked submucosal tumor such as gastrointestinal tumor. This case resulted in a positive positron emission tomography scan suggesting malignant neoplasm, but beta-catenin positivity on immunohistochemical staining separated MF from gastrointestinal stromal tumor and sclerosing mesenteritis. The clinical course of the patient was improved after surgical resection.

Keyword

Mesenteric fibromatosis; Colonic obstruction; Hydroureteronephrosis

MeSH Terms

beta Catenin
Colon
Colon, Sigmoid
Fibroma
Fibrosarcoma
Gastrointestinal Stromal Tumors
Gastrointestinal Tract
Humans
Panniculitis, Peritoneal
Positron-Emission Tomography
Ureter
beta Catenin