Gut Liver.  2007 Jun;1(1):68-73.

Endoscopic Ultrasonograpic Findings of Benign Mediastinal and Abdominal Lymphadenopathy Confirmed by EUS-guided Fine Needle Aspiration

• Song HJ
• Kim JO
• Eun SH
• Cho YD
• Jung IS
• Cheon YK
• Moon JH
• Lee JS
• Lee MS
• Shim CS
• Kim BS
• Jin SY

Abstract

BACKGROUND/AIMS: Distinguishing benign and malignant lymph nodes by the findings of endoscopic ultrasonography (EUS) is still controversial. We tried to evaluate EUS findings of benign mediastinal and abdominal lymphadenopathy (BLAP) confirmed by EUS-guided fine needle aspiration (FNA).
METHODS
A total of 37 patients with enlarged mediastinal or abdominal lymph nodes (diameter > or =1 cm) were enrolled and EUS-FNA was performed. Final diagnosis was based on FNA cytology and follow up imaging studies (CT scans or EUS).
RESULTS
Thirteen patients were confirmed to have BLAP by EUS-FNA. Causes of BLAP were as follows; (i) extrapulmonary tuberculosis in six cases including patients with postoperative states due to cervical cancer and advanced gastric cancer, (ii) Kikuchi disease in one case, (iii) hypereosinophilic syndrome in one case, (iv) reactive hyperplasia in five cases including patients with postoperative states due to thyroid cancer, lung cancer, and EGC with ESD. EUS findings of BLAP revealed that median lymph node size was 24.7 mm. Lymph nodes were oval or round shaped in 9 cases, sharp borders in 9 cases, hypoechoic echo pattern in 7 cases, heterogenous internal echo pattern in 7 cases. Other findings included internal septation, calcification, multiplicity, attachment to the gastrointestinal tract wall, and conglomeration.
CONCLUSIONS
EUS findings of BLAP were not different from those of malignant lymphadenopathy previously reported in other studies.

Keyword

Lymphadenopathy; Endoscopic ultrasonography, Fine needle aspiration

MeSH Terms

Biopsy, Fine-Needle*
Diagnosis
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Endosonography
Follow-Up Studies
Gastrointestinal Tract
Histiocytic Necrotizing Lymphadenitis
Humans
Hypereosinophilic Syndrome
Hyperplasia
Lung Neoplasms
Lymph Nodes
Lymphatic Diseases*
Stomach Neoplasms
Thyroid Neoplasms
Tuberculosis
Uterine Cervical Neoplasms