Gut Liver.  2007 Jun;1(1):12-21.

Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection as Treatments for Early Gastrointestinal Cancers in Western Countries

Affiliations
  • 1Operative Unit of Diagnostic and Therapeutic Endoscopy, Department of General and Specialized Surgery and Organ Transplantation "Paride Stefanini", University of Rome "La Sapienza", Rome, Italy.
  • 2Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
  • 3Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan. tgotoda@ncc.go.jp

Abstract

Early gastrointestinal cancers are defined as lesions limited to the mucosa or submucosa without invading the muscularis propria, regardless of the presence of lymph node metastases. Although the natural history of these diseases is basically alike worldwide, its management is quite different between the East and West; aggressive surgery is frequently adopted by Western surgeons, while less invasive techniques are adopted by Asian colleagues. These techniques include endoscopic mucosal resection and endoscopic submucosal dissection which are now accepted as treatments for early gastrointestinal cancers in selected cases. Recent advances in endoscopic detection and treatment techniques, especially in Japan and Korea, have prompted Western endoscopists to learn these techniques. This review addresses recent advances regarding endoscopic resections of early gastrointestinal cancers, which promoted its use in Western countries. In addition, prospective studies on endoscopic resection in Western countries are also described.

Keyword

Endoscopic resection; Gastrointestinal cancer; West

MeSH Terms

Asian Continental Ancestry Group
Gastrointestinal Neoplasms*
Humans
Japan
Korea
Lymph Nodes
Mucous Membrane
Natural History
Neoplasm Metastasis
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