Endocrinol Metab.  2012 Sep;27(3):244-246. 10.3803/EnM.2012.27.3.244.

A Case of Diabetic Mastopathy

• Lee SH
• Kim BM
• Kim JW
• Hong MK
• Hyeon S
• Kim MY
• Kim J
• Ahn J

• KMID: 2282410
• DOI: http://doi.org/10.3803/EnM.2012.27.3.244

Abstract

Diabetic mastopathy is an unusual fibroinflammatory breast lesion that is characteristically presented in premenopausal women with long-standing diabetes with multiple microvascular complications. This patient was a 49-year-old postmenopausal woman with diabetic nephropathy, neuropathy, and retinopathy. Although palpable mass was detected on the left breast, an ultrasonography could not distinguish it from breast cancer. Excisional biopsy was conducted. Histological findings indicated diabetic mastopathy with keloid-like fibrosis, perivascular lymphocytic infiltration, and lymphocytic lobulitis without evidence of malignancy. After excision, there has been no recurrence until now.

Keyword

Diabetic mastopathy; Diabetes

MeSH Terms

Biopsy
Breast
Breast Neoplasms
Diabetic Nephropathies
Female
Fibrosis
Humans
Middle Aged
Recurrence

Figure

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  Fig. 1 Ultrasonography shows 1.8 cm sized heterogeneous irregular hypoechoic nodules in (A) right and (B) left breast.

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  Fig. 2 (A) Histopathological findings (H&E stain, × 100) show that lymphocytic infiltration around the lobules and ducts. (B) Markedly increased keloid-like collagen and enlarged epithelioid fibroblasts (H&E stain, × 200).

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