Korean J Pediatr.  2010 Feb;53(2):239-243. 10.3345/kjp.2010.53.2.239.

High-dose caspofungin salvage in a very-low-birth-weight infant with refractory candidemia

Affiliations
  • 1Department of Pediatics, Busan St. Mary's Medical Center, Busan, Korea. ksm7090@hanmail.net
  • 2Department of Radiology, Busan St. Mary's Medical Center, Busan, Korea.
  • 3Department of clinical pathology, Busan St. Mary's Medical Center, Busan, Korea.

Abstract

Candidiasis is one of the most common causes of late-onset infection among very-low-birth-weight infants (VLBW) in most neonatal intensive care units and is associated with significant morbidity and mortality. Standard therapy consists of the administration of amphotericin B, amphotericin B complex, and fluconazole. In many cases, candidiasis is not easily eradicated, despite the administration of these drugs. We report our experience of the addition of high-dose caspofungin to the conventional antifungal drugs in a VLBW infant with refractory candidemia.

Keyword

Candidiasis; Caspofungin; Infant; Very low birth weight

MeSH Terms

Amphotericin B
Candidemia
Candidiasis
Echinocandins
Fluconazole
Humans
Infant
Infant, Newborn
Infant, Very Low Birth Weight
Intensive Care Units, Neonatal
Amphotericin B
Echinocandins
Fluconazole
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