Korean J Perinatol.
2007 Jun;18(2):168-172.
A Case of Preeclampsia Complicating a Pregnancy with Malignant Neurofibromatosis
- Affiliations
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- 1Department of Obstetrics and Gynecology, College of Medicine, Sunchunhyang University, Bucheon Hospital, Korea. heeobgy@schbc.ac.kr
- 2Department of Obstetrics and Gynecology, College of Medicine, Sunchunhyang University, Seoul Hospital, Korea.
Abstract
- Neurofibromatosis type 1 (NF-1) is one of the most common genetic disorders, occurring once in every 4000 births. The prevalence of neurofibromatosis associated with pregnancy was one in 5000~18500 deliveries. Higher rates of maternal and neonatal complications have been reported in NF-1 patients including as hypertension, intrauterine growth restriction (IUGR), preterm labor, stillbirth and cesarean section rates. Thus, pregnant patients with NF-1 are required close antenatal observation at high risk tertiary centers in order to detect complication early. We report a case of malignant neurofibromatosis associated with pregnancy with a review of literature.
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