Korean J Pediatr.
2004 Dec;47(12):1347-1350.
A Case of Childhood Acute Lymphoblastic Leukemia with Monosomy 20 and Parotid Gland Involvement
- Affiliations
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- 1Department of Pediatrics, Keimyung University, School of Medicine, Daegu, Korea. kimhs@dsmc.or.kr
- 2Department of Laboratory Medicine, Keimyung University, School of Medicine, Daegu, Korea.
- 3Department of Pathology, Keimyung University, School of Medicine, Daegu, Korea.
Abstract
- Hypodiploidy exists in 3-15% of patients with childhood acute lymphoblastic leukemia(ALL) and is associated with a poor prognosis. Monosomy 7 and monosomy 20 account for most karyotypic abnormalities in patients in whom whole chromosomes are lost and their incidences are rare. Parotid tumors in the pediatric age group are unusual and in 1996, there was a case of invasion of the parotid glands of ALL in a 6-year-old boy with swelling of both parotid glands. But invasion of acute lymphocytic leukemia to the parotid gland has not yet been reported in Korea. Here, we report a 33 month-old boy with swelling of both parotid glands who was diagnosed to have ALL with monosomy 20 & parotid gland invasion.
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