Korean J Pediatr Infect Dis.  2014 Dec;21(3):219-224. 10.14776/kjpid.2014.21.3.219.

A Case of Late Onset Neonatal Bacteremia and Meningitis Caused by Streptococcus lutetiensis

• Kim JS
• Hong YR
• Yang HY
• Oh CE

• KMID: 2279098
• DOI: http://doi.org/10.14776/kjpid.2014.21.3.219

Abstract

Invasive infection of the Streptococcus bovis group in a neonate is rare. In cases reported to date, the pathogen of neonatal S. bovis infections is usually Streptococcus gallolyticus subsp. pasteurianus (S. bovis biotype II/2). Streptococcus lutetiensis (S. bovis biotype II/1) was identified using 16S rRNA and tuf gene sequence analysis of the isolates from blood and cerebrospinal fluid (CSF) of a fever-presenting 28-day-old male. Blood culture analysis was performed using automatic equipment (VITEK 2) and identified Streptococcus infantarius supsp. infantarius, yet we were unable to get accurate results from the CSF culture. The fever subsided on the second day of hospitalization, and the patient was discharged without neurologic complication after 14 days of antibiotic therapy. In this case, we were able to accurately identify the pathogen using molecular genetic methods. To our knowledge, this is the first case of late onset neonatal bacteremia and meningitis caused by S. lutetiensis.

Keyword

Streptococcus bovis; Newborn; Bacteremia; Meningitis

MeSH Terms

Bacteremia*
Cerebrospinal Fluid
Fever
Hospitalization
Humans
Infant, Newborn
Male
Meningitis*
Molecular Biology
Sequence Analysis
Streptococcus bovis
Streptococcus*

Reference

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