Korean J Pediatr Infect Dis.  2014 Dec;21(3):167-173. 10.14776/kjpid.2014.21.3.167.

The Changes in the Outbreak of Rotavirus Gastroenteritis in Children after Introduction of Rotavirus Vaccines: A Retrospective Study at a Tertiary Hospital

• Park DK
• Chung JY

• KMID: 2279084
• DOI: http://doi.org/10.14776/kjpid.2014.21.3.167

Abstract

PURPOSE
This study aimed to examine the changes in the outbreak of acute gastroenteritis, rotavirus gastroenteritis after the introduction of the rotavirus vaccine in Korea.
METHODS
The current study investigated the number of inpatients in the pediatric ward of Inje University Sanggye Paik Hospital during the periods of 2005-2006 and 2011-2012. A retrospective analysis was conducted on the medical records of 2,840 patients <5 years of age who were hospitalized at Inje University Sanggye Paik Hospital in these time periods.
RESULTS
When we compared 2 separate sets of data from before (2005-2006) and after (2011-2012) vaccine introduction, there were statistically significant decreases in the number of patients who were hospitalized for acute gastroenteritis across all of the groups of patients <5 years of age except those <2 months of age. The number of patients with rotavirus gastroenteritis in all age groups declined except for children <2 months of age and those 2-5 months of age.
CONCLUSION
These results show that after the introduction of a rotavirus vaccine in Korea, the incidence of rotavirus gastroenteritis decreased in 6-59-month-old patients hospitalized for acute gastroenteritis.

Keyword

Rotavirus; Vaccination; Gastroenteritis

MeSH Terms

Child*
Gastroenteritis*
Humans
Incidence
Inpatients
Korea
Medical Records
Retrospective Studies*
Rotavirus Vaccines*
Rotavirus*
Tertiary Care Centers*
Vaccination
Rotavirus Vaccines

Figure

• 

  Fig. 1. Acute gastroenteritis-related hospitalization.

• 

  Fig. 2. Monthly distributions of rotavirus gastroenteritis.

Reference

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