Korean J Pediatr.  2005 Oct;48(10):1139-1142.

Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older

Affiliations
  • 1Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea. yongpw@hanmail.net
  • 2Department of Pediatrics, Catholic University, Seoul, Korea.
  • 3Department of Pediatrics, University of Ulsan, Seoul, Korea.
  • 4Department of Pediatrics, Soonchunhyang University, Buchun, Korea.
  • 5Department of Pediatrics, Kyunghee University, Seoul, Korea.
  • 6Department of Pediatrics, Chonnam National University, Kwangju, Korea.
  • 7Department of Pediatrics, Keimyung University, Daegu, Korea.
  • 8Department of Pediatrics, Kyungpook National University, Daegu, Busan, Korea.
  • 9Department of Pediatrics, Sungkyunkwan University, Seoul, Korea.
  • 10Department of Pediatrics, Seoul National University, Seoul, Korea.

Abstract

PURPOSE
The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease (KD) in children 8 years of age and older. METHODS: For the epidemiologic study of KD in Korea, data of total 15, 692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age. RESULTS: 211 patients 8 years of age and older (1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9: 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial (CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction. CONCLUSION: Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities (25.4%: 19.8%) and CA aneurysms (7.6%: 4.0%).

Keyword

Kawasaki disease; Mucocutaneous lymph node syndrome; Coronary aneurysm; Epidemiology; Child

MeSH Terms

Aneurysm
Child*
Coronary Aneurysm
Echocardiography
Epidemiologic Studies*
Epidemiology
Humans
Incidence
Korea
Mucocutaneous Lymph Node Syndrome*
Myocardial Infarction
Prevalence
Recurrence
Retrospective Studies
Siblings
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