Clin Exp Otorhinolaryngol.  2012 Mar;5(1):49-52.

Giant Cell Tumor of the Mandible

• Park SR
• Chung SM
• Lim JY
• Choi EC

Abstract

A 53-year-old woman presented with left mandibular area pain, trismus, and facial numbness that had persisted for 4 years. Physical examination revealed a 3x5 cm, hard, non-tender, and round mass on the left mandibular area. Computed tomography and magnetic resonance imaging revealed an expansile tumor involving the left mandibular ramus and temporomandibular joint area with bone destruction, extending to the base of middle cranial fossa and left zygomatic bone. The mass at the segment of left mandible and zygomatic bone, and base of middle cranial fossa was removed. Pathological examination of the mass revealed a giant cell tumor. The defect was reconstructed with iliac bone for the mandible and temporal bone and fascia for the cranial bone and dura. The case is described along with a review of the literature.

Keyword

Giant cell tumor; Skull; Mandible

MeSH Terms

Cranial Fossa, Middle
Fascia
Female
Giant Cell Tumors
Giant Cells
Humans
Hypesthesia
Magnetic Resonance Imaging
Mandible
Middle Aged
Physical Examination
Skull
Temporal Bone
Temporomandibular Joint
Trismus

Figure

• 

  Fig. 1 CT findings showing the TMJ lesion (arrow) and extension to the base of middle cranial fossa (arrowhead).

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  Fig. 2 Facial MRI findings revealing 5×3 cm sized heterogenous, well-defined and expansile mass is located at the condylar fossa (arrow).

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  Fig. 3 (A) The mass lesion is exposed from infraparotid space (i) and from supraparotid space (ii). (B) After mass resection and segmental mandibulectomy, the defect is observed from infraparotid space (i) and from supraparotid space (ii).

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  Fig. 4 (A) Reconstruction of cranial bone and dura with left temporalis bone and fascia. (B) Reconstruction of mandible A with iliac bone.

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  Fig. 5 Evenly distributed multinucleated giant cell with surrounding stroma made up of spindle cells are shown, which were consistent with GCT.

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  Fig. 6 (A) Postoperative CT taken 1 year after the operation reveals no sign of recurrence. (B) The facial contour and masticatory function was well preserved, except for the lateralization of the mandible on the opening of mouth.

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