Korean J Pathol.
2010 Feb;44(1):87-91.
A Case of Gastric Carcinosarcoma with Neuroendocrine and Smooth Muscle Differentiation
- Affiliations
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- 1Department of Pathology, Hanyang University College of Medicine, Seoul, Korea. sspaik@hanyang.ac.kr
Abstract
- Carcinosarcoma of the stomach is a rarely occurring malignant biphasic tumor that consists of both carcinomatous and sarcomatous components simultaneously in a single tumor. The common carcinoma component is tubular or papillary adenocarcinoma and the mesenchymal sarcomatous components are variable and these include leiomyosarcoma, rhabdomyosarcoma, osteosarcoma and chondrosarcoma. However, neuroendocrine carcinomatous differentiation in the carcinomatous component is extremely rare. We present here a rare gastric carcinosarcoma that demonstrated neuroendocrine carcinomatous and leiomyosarcomatous differentiation in a 47-year-old man.
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