Korean J Pathol.  2011 Aug;45(4):412-416.

Parotid Gland Carcinosarcoma with Osteosarcoma as a Sarcomatous Component: A Case Report with Fine Needle Aspiration Cytologic Findings

• Jang SM
• Jun YJ
• Han H
• Jang KS
• Paik SS

Abstract

Carcinosarcoma of the salivary glands is a rare malignant tumor showing both malignant epithelial and mesenchymal components. Herein, we present a carcinosarcoma of the parotid gland in a 67-year-old man consisting of osteosarcoma and adenocarcinoma components with fine needle aspiration cytological findings. The tumor was composed predominantly of osteosarcoma and small areas of adenocarcinomatous components and a hyalinized nodule reminiscent of pleomorphic adenoma. The tumor showed infiltrative growth features with perineural, lymphatic, and vascular invasion. Despite postoperative adjuvant radiation therapy, multiple metastatic lesions occurred in the both lungs 5 months after surgery. As salivary gland carcinosarcoma has been known to demonstrate highly aggressive behavior, an accurate pathological diagnosis is prerequisite for appropriate treatment.

Keyword

Carcinosarcoma; Osteosarcoma; Adenocarcinoma; Fine-needle aspiration cytology; Parotid gland

MeSH Terms

Adenocarcinoma
Adenoma, Pleomorphic
Aged
Biopsy, Fine-Needle
Carcinosarcoma
Humans
Hyalin
Lung
Osteosarcoma
Parotid Gland
Salivary Glands