Korean J Otorhinolaryngol-Head Neck Surg.
2012 Nov;55(11):701-706. 10.3342/kjorl-hns.2012.55.11.701.
Comparison of Voice Outcomes in Early Glottic Cancer Patients after Laser Surgery or Radiotherapy
- Affiliations
-
- 1Department of Otorhinolaryngology Head and Neck Surgery, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
- 2Department of Otorhinolaryngology Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- 3Department of Otorhinolaryngology Head and Neck Surgery, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. irin0207@daum.net
- KMID: 2277425
- DOI: http://doi.org/10.3342/kjorl-hns.2012.55.11.701
Abstract
- BACKGROUND AND OBJECTIVES
Radiotherapy and laser surgery are the main treatment modalities for early glottic cancer. However, which treatment has better voice outcome is unclear. Few studies have considered the effect of radiation dose on voice outcomes after radiotherapy. The purpose of this study was to compare voice outcomes in early glottic cancer patients between two treatment modalities and to identify whether radiation dose affects voice outcomes.
SUBJECTS AND METHOD
From January 1995 to December 2010, 66 patients with the early glottic cancer who underwent laser surgery (n=27) or radiotherapy (n=39) were retrospectively investigated. Voice quality was assessed using Computerized Speech Lab and F0, Jitter, Shimmer and noise to harmonic ratio were evaluated. For aerodynamic test, maximum phonation time was also evaluated.
RESULTS
F0 differed statistically between the laser surgery group and radiotherapy group. In laser surgery group, F0 was elevated after surgery. On the other hand, F0 decreased statistically after radiotherapy. In the radiotherapy group, the dose was statistically different between the lower and higher dose groups. In T2 stage disease, which received a higher radiation dose, voice outcomes were poorer than in T1a or T1b stage diseases.
CONCLUSION
In early glottic cancer, F0 differed statistically between the laser surgery group and the radiotherapy group: F0 decreased statistically after radiotherapy. In the radiotherapy group, voice quality was affected by radiation dose as the higher dose resulted in poorer voice outcomes.
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