Korean J Pathol.
2013 Aug;47(4):388-391.
Spindle Cell Rhabdomyosacoma of Uterus: A Case Study
- Affiliations
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- 1Department of Obstetrics and Gynecology, Eulji University School of Medicine, Seoul, Korea.
- 2Department of Pathology, Eulji University School of Medicine, Seoul, Korea. kek7402@eulji.ac.kr
Abstract
- Uterine rhabdomyosarcoma (RMS) typically presents as a mixed epithelial and mesenchymal tumors. Pure RMSs of the female genital tract are uncommon. Spindle cell variant of RMS is a rare morphologic subtype of embryonal RMS and mostly occurs in the paratesticular region of children. Here, we present a case of uterine spindle cell RMS in a 76-year-old woman. The tumor, 20x15x7 cm in size, was highly necrotic and adherent to the colon and rectum. Tumor cells were mostly spindle-shaped, and isolated rhabdomyoblasts were scattered. Immunohistochemical stains for myoglobin and myo-D1 showed diffuse positivity for tumor cells. The patient died only of disease three months after diagnosis.