Korean J Otorhinolaryngol-Head Neck Surg.
2008 Dec;51(12):1151-1154.
A Case Report of Lou Gehrig's Disease Presenting with Rhinolalia Aperta in Its Early Stage
- Affiliations
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- 1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Jinju, Korea. syjeon@nongae.gsnu.ac.kr
- 2Institute of Health Science, Gyeongsang National University, Jinju, Korea.
Abstract
- Lou Gehrig's disease, also called amyotrophic lateral sclerosis, is a chronic progressive motor neuron disease of an unknown etiology, characterized by upper and lower motor neuron degeneration with a resultant progressive weakness of bulbar muscles or the extremities. The early symptoms may include twitching, cramping, muscle weakness of distal extremities and slurred nasal speech. Rhinolalia aperta is abnormal speech attributable to inadequate velopharyngeal closure. Hypernasality is thequality of voice in which the emission of air through the nose is excessive due to velopharyngeal insufficiency so that the voice is highpitched and speech intelligibility deteriorates. We experienced a rare case of Lou Gehrig's disease presenting with rhinolia aperta in its early stage. We report the case with a literature review.
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