Korean J Otolaryngol-Head Neck Surg.
2006 Apr;49(4):447-450.
A Case of Hereditary Hemorrhagic Telangiectasia Managed with Intranasal Topical Estrogen
- Affiliations
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- 1Department of Otolaryngology, Ajou University School of Medicine, Seoul, Korea. entkhj@ajou.ac.kr
Abstract
- Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder affecting blood vessels of the skin, mucous membrane and viscera. It is characterized by a clinical triad of multiple telangiectasia, recurrent hemorrhages and familial occurrence. In 80% of patients, epistaxia is the first presenting symptom. It can have a massive impact on the quality of life of those affected. Otolaryngologists should be familiar with this disease because of its potential systemic complication. Recently, we have experienced a 69 year old female complaining of melena and recurrent epistaxis for 20 years. Epistaxis was successfully managed with topical estrogen ointment.
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