Korean J Otolaryngol-Head Neck Surg.  2002 Mar;45(3):293-295.

A Case of Cholesterol Granuloma of the Sphenoid Sinus

• Jun JH
• Park JY
• Yeo CK
• Shon KR

Abstract

Cholesterol granuloma is usually described in association with middle ear diseases, but has also been reported to be found in the paranasal sinuses and orbit. It is currently thought that impaired drainage, hemorrhage and inadequate ventilation play significant roles in its pathogenesis. Histopathologic examination of cholesterol granuloma shows abundant foreign body giant cells, cholesterol crystal clefts, histiocytes surrounded by a dense fibrous capsule. We report our endoscopic surgical experience in one female patient with a large cholesterol granuloma of the sphenoid sinus presenting bilateral visual involvement and brain invasion.

Keyword

Cholesterol granuloma; Sphenoid sinus

MeSH Terms

Brain
Cholesterol*
Drainage
Ear, Middle
Female
Giant Cells, Foreign-Body
Granuloma*
Hemorrhage
Histiocytes
Humans
Orbit
Paranasal Sinuses
Sphenoid Sinus*
Ventilation
Cholesterol