Korean J Otolaryngol-Head Neck Surg.
2002 Feb;45(2):182-186.
Combination Therapy with Endoscopic Removal and Ambisome for Rhinocerebral Aspergillosis Invading Frontal Lobe: Report of a Case
- Affiliations
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- 1Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea. jhsent@cmc.cuk.ac.kr
Abstract
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The rhinocerebral aspergillosis invading sinuses and CNS is known to be a fatal desease in immunocompromised patients. The management principle of rhinocerebral aspergillosis is often by extensive surgical removal through craniotomy combined with amphotericin B therapy, and endoscopic removal had not been reported until now. We report in this study a case of rhinocerebral aspergillosis invading the left frontal sinus and the left frontal lobe which were treated by the combination therapy of endoscopic removal and antifungal agents.