Korean J Pathol.  1997 Jan;31(1):34-39.

Renal Dysplasia: A Clinicopathologic Review of Six Cases

Affiliations
  • 1Department of Pathology, Chungnam National University School of Medicine, Taegeon 301-131, Korea.

Abstract

Renal dysplasia results from aberrant histogenesis in metanephric differentiation. It is characterized morphologically by abnormal organization and a persistence of primitive structures, such as cartilage, undifferentiated mesenchyme, and immature tubules. Six cases of renal dysplasia from five children and one adult are reviewed. Five patients were female and one patient was male. The chief complaint was urinary incontinence in four patients, dysuria in one patient, and the sixth patient suffered from vesicoureteral reflux. No evidence of family history of renal dysplasia in any patient was seen. According to Risdon's classification, three cases were hypoplastic dysplasia, one case was dysplasia in a duplex system, one case was dysplasia in a triplex system, and one case was dysplasia with vesicoureteral reflux. The ipsilateral ectopic ureteral orifice was identified in four patients, two of which drained into a Gartner's duct cyst, and the orifice was suggested in one patient. On histologic examination, all cases showed primitive ducts surrounded by concentrically arranged primitive mesenchyme. Nests of metaplastic cartilage were observed within the stroma in three of the six cases.

Keyword

Renal dysplasia; Risdon's classification; Duplex system; Triplex system, Gartner's duct cyst

MeSH Terms

Adult
Cartilage
Child
Classification
Dysuria
Female
Humans
Male
Mesoderm
Ureter
Urinary Incontinence
Vesico-Ureteral Reflux
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