Korean J Pathol.  2003 Jun;37(3):151-158.

Experimental Liver Disease Models of Rats: Morphological Characteristics

• Park DY
• Suh KS

Abstract

Experimental liver disease models of rats have many similarities with those of humans, especially in morphological characteristics. Rat liver disease models can be categorized as models of hepatic fibrosis, hepatic stem cell and hepatocarcinogenesis. The purpose of this article is to review experimental liver disease models, with a major emphasis on morphologic features, including routine morphological, immunohistochemical, and electron microscopic features.

MeSH Terms

Animals
Fibrosis
Humans
Liver Diseases*
Liver*
Rats*
Stem Cells