Korean J Otolaryngol-Head Neck Surg.  2000 Jan;43(1):36-39.

Histochemical Localization of NADPH-Diaphorase in the Rat Vomeronasal Organ

Affiliations
  • 1Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Yeungnam University, Taegu, Korea.

Abstract

BACKGROUND AND OBJECTIVES
The vomeronasal organ of the rat is a chemosensory organ located at the nasal septum. The distribution of nitroxidergic nerve fiber in olfactory system such as olfactory bulb, accessory olfactory bulb and olfactory epithelium was well documented, but vomeronasal organ which is a component of olfactory system and the receptor structure of the accessory olfactory system was rarely reported and discorded. The aim of this study was to determine the distribution and role of nitirc oxide (NO) in the rat vomeronasal organ using NADPH-diaphorase histochemistry.
MATERIALS AND METHODS
Histochemical staining for NADPH-diaphorase in the rat vomeronasal organ was done.
RESULTS
The NADPH-diaphorase positive reaction was observed in the blood vessels, nerve fibers around vessels and submucosal glands of vomeronasal organ. However, receptor area which is generally called the neuroepithelium and receptor free area were not seen.
CONCLUSION
These results suggest that NADPH-diaphorase positive reaction shows tissue specific expression in the rat vomeronasal organ.

Keyword

Vomeronasal organ; NADPH-diaphorase; NO; Rat

MeSH Terms

Animals
Blood Vessels
Nasal Septum
Nerve Fibers
Olfactory Bulb
Olfactory Mucosa
Rats*
Vomeronasal Organ*
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