- Effects of Mesenchymal Stem Cells Treatment on Radiation-Induced Proctitis in Rats
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Kim WH, Yoo JH, Yoo IK, Kwon CI, Hong SP
- KMID: 2539559
- Yonsei Med J.
- 2023 Mar;64(3):167-174.
- doi: 10.3349/ymj.2022.0342
Purpose: There are no effective treatment methods with which to control complications of radiation proctitis with fistula or recurrent bleeding following radiation treatment for prostate, cervical, or rectal cancer. Mesenchymal... -
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- Efficacy and Safety of Human Bone Marrow-Derived Mesenchymal Stem Cells according to Injection Route and Dose in a Chronic Kidney Disease Rat Model
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Chae HK, Suh N, Jang MJ, Kim YS, Kim BH, Aum J, Shin HC, You D, Hong B, Park HK, Kim CS
- KMID: 2539622
- Int J Stem Cells.
- 2023 Feb;16(1):66-77.
- doi: 10.15283/ijsc21146
Background and Objectives: We compared the efficacy and safety of human bone marrow-derived mesenchymal stem cells (hBMSC), delivered at different doses and via different injection routes in an animal model... -
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- Environmental measures and healthcare service utilization against laboratory animal allergy in Korean laboratory animal researchers
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Kang SY, Won HK, Park SY, Lee SM, Lee SP
- KMID: 2538967
- Allergy Asthma Respir Dis.
- 2023 Jan;11(1):18-25.
- doi: 10.4168/aard.2023.11.1.18
Purpose: This study aimed to evaluate the environmental measures and healthcare service utilization against laboratory animal allergy (LAA) in Korea. Methods: A total of 213 subjects who attended the 2018 Korean... -
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- Enhancing the Effect of Placental Extract on the Regeneration of Crush Injured Facial Nerve
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Lim GM, Cho GW, Ganesan CD, Choi JH, Ang MJ, Moon C, Jang CH
- KMID: 2537961
- Exp Neurobiol.
- 2022 Dec;31(6):419-430.
- doi: 10.5607/en22006
There is a scarcity of experimental studies on peripheral nerve regeneration using placental extract (PE). This study aimed to investigate the effects of topical PE application on recovery after crush... -
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- Morphological, ultrastructural, and biochemical changes induced by sodium fluoride in the tongue of adult male albino rat and the ameliorative effect of resveratrol
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El-Bestawy EM, Tolba AM, Rashad WA
- KMID: 2537468
- Anat Cell Biol.
- 2022 Dec;55(4):483-496.
- doi: 10.5115/acb.22.088
Little knowledge is available about the effects of fluoride exposure on the tongue. This study evaluated the effects of sodium fluoride (NaF) on the tongue ultrastructure and detected the ameliorative... -
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- Tissues toxicity attenuation by vitamin E on oxidative damage induced by diazinon
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Tahmasebi K, Jafari M, Heydari J, Asgari A, Salehi M, Khazaie S, Abedini MS
- KMID: 2539840
- Environ Anal Health Toxicol.
- 2022 Dec;37(4):e2022036.
- doi: 10.5620/eaht.2022036
Organophosphorus insecticides such as diazinon (DZN) are used worldwide in industry, veterinary practice, and agriculture. They may induce oxidative stress in different tissues. The use of antioxidants can protect tissues... -
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- Temporal Modulation of DNA Methylation and Gene Expression in Monolayer and 3D Spheroids of Dental Pulp Stem Cells during Osteogenic Differentiation: A Comparative Study
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Raik S, Thakur R, Rattan V, Kumar N, Pal A, Bhattacharyya S
- KMID: 2536457
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1267-1282.
- doi: 10.1007/s13770-022-00485-x
BACKGROUND: Human mesenchymal stem cells are being used for various regenerative applications in past decades. This study chronicled a temporal profile of the transcriptional pattern and promoter methylation status of the... -
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- Delayed-Onset Perforating Phenomenon in a Patient with Sorafenib-Induced Psoriasiform Eruption
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Song CH, Song SY, Kim JE, Ro YS, Ko JY
- KMID: 2536330
- Korean J Dermatol.
- 2022 Nov;60(9):628-630.
Sorafenib is an inhibitor of receptor tyrosine kinases and the rat sarcoma/mitogen-activated protein kinase (RAS/MAPK) pathway that is approved for the treatment of patients with metastatic hepatocellular carcinoma (HCC) and... -
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- Enhancement of bioactivity and osseointegration in Ti-6Al-4V orthodontic mini-screws coated with calcium phosphate on the TiO 2 nanotube layer
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Byeon SM, Kim HJ, Lee MH, Bae TS
- KMID: 2536334
- Korean J Orthod.
- 2022 Nov;52(6):412-419.
- doi: 10.4041/kjod22.118
Objective: This study evaluated the effect of cyclic pre-calcification treatment on the improvement of bioactivity and osseointegration of Ti-6Al-4V miniscrews. Methods: The experimental groups were: an untreated group (UT), an... -
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- Perioperative stress prolong post-surgical pain via miR-339-5p targeting oprm1 in the amygdala
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Zhu Y, Sun M, Liu P, Shao W, Xiong M, Xu B
- KMID: 2533982
- Korean J Pain.
- 2022 Oct;35(4):423-432.
- doi: 10.3344/kjp.2022.35.4.423
Background: The decreased expression of mu-opioid receptors (MOR) in the amygdala may be a key molecular in chronic post-surgical pain (CPSP). It is known that miR-339-5p expression in the amygdala... -
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- Impact of polystyrene microplastic exposure on lipid profile and oxidative stress status of male and female Wistar rats
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Nnoruka UC, Okonkwo CJ, Ilechukwu I, Okonkwo CJ, Belonwu DC
- KMID: 2534368
- Environ Anal Health Toxicol.
- 2022 Sep;37(3):e2022024.
- doi: 10.5620/eaht.2022024
Microplastics (MPs) are currently global environmental pollutants, and their associated health risks cannot be ignored. However, research on MP toxicity in mammals is limited. We investigated the effects of polystyrene... -
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- Anti-stress Effect of Octopus Cephalotocin in Rats
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Kim YJ, Jo S, Jung SH, Woo DH
- KMID: 2532836
- Exp Neurobiol.
- 2022 Aug;31(4):260-269.
- doi: 10.5607/en22010
Cephalotocin is a bioactivity-regulating peptide expressed in octopus (Octopus vulgaris). The peptide sequence of cephalotocin is very similar to the peptide sequence of mammalian vasopressin, and cephalotocin has been proposed... -
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- Enhanced Bone Regeneration by Bone Morphogenetic Protein-2 after Pretreatment with Low-Intensity Pulsed Ultrasound in Distraction Osteogenesis
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Han JJ, Yang HJ, Hwang SJ
- KMID: 2533922
- Tissue Eng Regen Med.
- 2022 Aug;19(4):871-886.
- doi: 10.1007/s13770-022-00457-1
BACKGROUND: Bone morphogenetic protein 2 (BMP-2) and low-intensity pulsed ultrasound (LIPUS) have been used to enhance bone healing in distraction osteogenesis (DO). The aim of this study was to assess... -
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- Ameliorative effect of Abeliophyllum distichum Nakai on benign prostatic hyperplasia in vitro and in vivo
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Choi YJ, Fan M, Tang Y, Moon S, Lee SH, Lee B, Bae SM, Lee SM, Kim EK
- KMID: 2532093
- Nutr Res Pract.
- 2022 Aug;16(4):419-434.
- doi: 10.4162/nrp.2022.16.4.419
BACKGROUND/OBJECTIVES: Benign prostatic hyperplasia (BPH) is the most common prostate disease and one of the most common chronic diseases caused by aging in men. On the other hand, there has... -
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- The Role of Alginate Hydrogels as a Potential Treatment Modality for Spinal Cord Injury: A Comprehensive Review of the Literature
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Jarrah R, Sammak SE, Onyedimma C, Ghaith AK, Moinuddin F, Bhandarkar AR, Siddiqui A, Madigan N, Bydon M
- KMID: 2531537
- Neurospine.
- 2022 Jun;19(2):272-280.
- doi: 10.14245/ns.2244186.093
Objective: To comprehensively characterize the utilization of alginate hydrogels as an alternative treatment modality for spinal cord injury (SCI). Methods: An extensive review of the published literature on studies using alginate... -
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- Comparative Morphological Study on Parotid and Submandibular Salivary Glands in Ovariectomized Rats
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Jeong MJ, Lee MH, Lim DS, Jeong M, Jeong SJ
- KMID: 2530860
- J Dent Hyg Sci.
- 2022 Jun;22(2):83-89.
- doi: 10.17135/jdhs.2022.22.2.83
Background: Estrogen deficiency affects the structure and function of the salivary glands in women, leading to a decrease in salivary secretion and a change in the composition of saliva. Previous... -
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- Chronic toxic effects of polystyrene microplastics on reproductive parameters of male rats
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Ilechukwu I, Ehigiator BE, Ben IO, Okonkwo CJ, Olorunfemi OS, Modo UE, Ilechukwu CE, Ohagwa NJ
- KMID: 2531408
- Environ Anal Health Toxicol.
- 2022 Jun;37(2):e2022015.
- doi: 10.5620/eaht.2022015
Microplastics have become a significant environmental concern. However, information on toxicity of microplastics in terrestrial organisms is limited. In this study, the chronic toxic effects of polystyrene microplastics (PS-MPs) on... -
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- Establishment of a novel experimental model of infected anal fistula in rat
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Zhao M, Wang A, Zhang L, Yu H
- KMID: 2530962
- Lab Anim Res.
- 2022 Jun;38(2):128-131.
- doi: 10.1186/s42826-022-00125-4
Refractory Crohn’s-like enterocutaneous fistula indicates the aggressive manifestation and lead to poor prognosis of patients. The development of multidisciplinary strategies for fistula administration largely subjects to the deficiency of animal... -
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- Assessment of Bacterial Communities Within the Biofilm of Bladder Calculi in the Neurogenic Bladder Rat Model Following Spinal Cord Injury
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Lee JW, Lee SS, Yang SH, Choe HS
- KMID: 2528263
- Int Neurourol J.
- 2022 Mar;26(1):26-30.
- doi: 10.5213/inj.2142182.091
Purpose: To develop a rat model of bladder calculi in the neurogenic bladder following spinal cord injury (SCI) and assess bacterial communities within the biofilm of bladder calculi using denaturing... -
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- Peripheral Neuropathy Phenotyping in Rat Models of Type 2 Diabetes Mellitus: Evaluating Uptake of the Neurodiab Guidelines and Identifying Future Directions
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Hossain MJ, Kendig MD, Letton ME, Morris MJ, Arnold R
- KMID: 2527715
- Diabetes Metab J.
- 2022 Mar;46(2):198-221.
- doi: 10.4093/dmj.2021.0347
Diabetic peripheral neuropathy (DPN) affects over half of type 2 diabetes mellitus (T2DM) patients, with an urgent need for effective pharmacotherapies. While many rat and mouse models of T2DM exist,... -
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