A Case of Spontaneous Regression of Nasal Angiofibroma

Lee, Nam Soo; Choe, Jae Hyuck; Sun, Sung Wook

Abstract

The angiofibroma is a highly vascular and histologically benign neoplasm that appears predominantly in adolescent males. Although histologically benign, this tumor frequently has characteristic pattern of locally aggressive growth and a tendency toward base of skull and intracranial invasion. The subject of spontaneous regression of angiofibroma has been the topic of several articles discussing its hormonal dependency. Some authors argued that the tendency of this tumor to undergo remission at the time of sexual maturity was possibly due to hormonal influence. A number of recent studies have also dealt with hormonal receptors of angiofibroma tissue. In this study, we report a recent case of spontaneous remission of nasal angiofibroma found in a pregnant woman. For this case, we assumed that hormonal changes related to pregnancy contributed to the involution of this tumor, thus supporting the theory of hormonal influence and the possibility of spontaneous regression.