Korean J Obstet Gynecol.  2012 Dec;55(12):1006-1009. 10.5468/KJOG.2012.55.12.1006.

Peritoneal dissemination of follicular carcinoma arising from struma ovarii in a pregnant woman

• Choi BR
• Kim BW
• Yoon SO
• Kim YT
• Lee S
• Kim JH

• KMID: 2274215
• DOI: http://doi.org/10.5468/KJOG.2012.55.12.1006

Abstract

Struma ovarii is defined as a rare monodermal form of ovarian teratoma that occupies more than 50% of thyroid tissue. Only 2% of struma ovarii display malignant histology, most of which is revealed as papillary carcinoma type. Follicular carcinoma originating from malignant struma ovarii is rarely reported. We report a case of a pregnant woman diagnosed with peritoneal dissemination of follicular carcinoma arising from struma ovarii.

Keyword

Struma ovarii; Follicular carcinoma; Peritoneal dissemination; Pregnancy

MeSH Terms

Carcinoma, Papillary
Female
Humans
Pregnancy
Pregnant Women
Struma Ovarii
Teratoma
Thyroid Gland

Figure

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  Fig. 1 Pelvic magnetic resonance imaging reveals (A) 4.5 × 3.0 cm sized right parovarian solid tumor, (B) an intrauterine gestational sac containing a fetal pole and 2.5 × 2.5 cm sized left parovarian solid tumor and 1.5 × 1.0 cm sized metastatic lesion in the pelvic cavity.

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  Fig. 2 Follicular thyroid type carcinoma arising in struma ovarii. (A) Peritoneal mass: tumor is enveloped by fibrous capsule and composed of closely packed small- and medium-sized follicles of thyroid gland (H&E, ×12). (B) Follicular carcinoma demonstrating vascular invasion. Tumor plug is present within the blood vessel located outside the fibrous capsule (H&E, ×100). (C) Mature cystic teratoma resected 5 years ago. Lesion consists of mature tissue resembling epidermis in lower left side and macro- and microfollicles of thyroid tissue in upper right side (H&E, ×40).

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