Korean J Obstet Gynecol.  2012 Dec;55(12):1001-1005. 10.5468/KJOG.2012.55.12.1001.

A case of ovarian cancer developed in Mayer-Rokitansky-Kuster-Hauser syndrome: Innate carcinogenesis of ovarian cancer

• Ko AR
• Kim JH
• Park SY
• Jeon YE
• Kim SJ
• Rhim CC
• Kang JB
• Park YH

• KMID: 2274214
• DOI: http://doi.org/10.5468/KJOG.2012.55.12.1001

Abstract

Vaginal aplasia is an unusual congenital anomaly of the genital tract with an incidence of 1 in 4,000 female births. The vast majority of the cases are part of Mayer-Rokitansky-Kuster-Hauser syndrome (MRKHs). In this syndrome, while the vagina is absent and the uterus is missing or extremely rudimentary, the ovarian function is normal and the secondary sexual characteristics are normally developed. The aim of the study is to present a case of ovarian cancer that developed on the ovary of a woman with MRKH syndrome.

Keyword

Mayer-Rokitansky-Kuster-Hauser syndrome; Ovarian cancer; Absent vagina

MeSH Terms

Abnormalities, Multiple
Female
Humans
Incidence
Kidney
Mullerian Ducts
Ovarian Neoplasms
Ovary
Parturition
Somites
Spine
Uterus
Vagina
Abnormalities, Multiple
Kidney
Mullerian Ducts
Somites
Spine
Uterus
Vagina

Figure

• 

  Fig. 1 A computed tomography scan shows rim-enhancing ovarian mass with solid part in pelvic cavity in patient with Mayer-Rokitansky-Küster-Hauser syndrome.

• 

  Fig. 2 Right ovary contains solid nodule composed of gray tan friable tissue and multiple cysts which are filled with serous and hemorrhagic fluid. Two triangular small rudimentary uteruses are seen in the center.

• 

  Fig. 3 Serous carcinoma of the ovary illustrates poor differentiation (H&E, ×100).

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