Korean J Obstet Gynecol.  2011 Nov;54(11):712-716. 10.5468/KJOG.2011.54.11.712.

A case of myxoid leiomyosarcoma of uterus occurring in a 5-year-old girl: A case report and literature review

Affiliations
  • 1Department of Obstetrics and Gynecology, Wonkwang University College of Medicine, Iksan, Korea. brkim21@lycos.co.kr
  • 2Department of Pathology, Wonkwang University College of Medicine, Iksan, Korea.

Abstract

Myxoid leiomyosarcoma of the uterus is a variant of leiomyosarcoma characterized by a large amount of myxomatous stroma and low mitotic counts with minimal cellular atypia but with subsequent malignant course. These tumors have a striking myxoid appearance and exhibit highly malignant behavior despite their low mitotic index. We report a first case of myxoid leiomyosarcoma of the uterus occurring in a young child with brief review of literatures.

Keyword

Myxoid leiomyosarcoma; Uterus; A young child

MeSH Terms

Child
Humans
Leiomyosarcoma
Mitotic Index
Preschool Child
Strikes, Employee
Uterus

Figure

  • Fig. 1 (A) Abdominopelvic computed tomographic scan after enhancement show 12.3 × 11.8 cm sized, heterogenous enhancing solid mass in abdominal cavity (M, mass; B, bladder). (B) The upper portion of the resected tumor showing gelatinous consistency (arrow).

  • Fig. 2 The smooth muscle cells are widely separated by myxoid material & increased mitotic figures (arrow) (A, H&E, ×200; B, H&E, ×400).

  • Fig. 3 (A) Immunohistochemical staining of smooth muscle cell actin (×400). (B) Immunohistochemical staining of vimentin (×400). (C) A large amount of myxoid matrix with cells forming an interanastomosing filigree pattern (alcian-blue, ×400).


Reference

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