Korean J Obstet Gynecol.  2009 Apr;52(4):391-399.

Ischemic perinatal stroke

• Roh CR

Abstract

Ischemic perinatal stroke occurring around the time of delivery is increasingly recognized as a cause of neurological disability in children. Surprisingly, the incidence of arterial infarction in neonates is as high as the annual incidence of large-vessel ischemic stroke in adults. Neonatal seizure is the most common clinical finding that triggers assessment. In other children, ischemic perinatal stroke is recognized only retrospectively with emerging hemiparesis or seizures after the early months of life. The outcome of ischemic perinatal stroke is variable and depends on severity, anatomic localization and other factors not yet well characterized. There is much to be learned about the natural history of ischemic perinatal stroke and there is as yet no evidence-based strategy for prevention or treatment. The incidence, clinical presentation, pathogenesis, risk factors and outcomes of this disorder are reviewed.

Keyword

Ischemic perinatal stroke; Seizure

MeSH Terms

Adult
Child
Humans
Incidence
Infant, Newborn
Infarction
Natural History
Paresis
Retrospective Studies
Risk Factors
Seizures
Stroke