Korean J Obstet Gynecol.
2008 Nov;51(11):1396-1401.
A case of aggressive angiomyxoma of the vulva
- Affiliations
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- 1Department of Obstetrics and Gynecology, Incheon st. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. tekim@catholic.ac.kr
- 2Department of Pathology, Incheon st. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Abstract
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Aggressive angiomyxoma is an uncommon soft-tissue neoplasm which affects the pelvis and genital organs of the young female predominantly. This tumor has a high tendency of local recurrence, but it usually does not develop metastasis. Although surgical excision with wide tumor-free margins may be necessary to obtain a complete cure, some of patients experience local recurrences. Many of the tumors are estrogen receptor (ER) and progesterone receptor (PR) positive and medical therapy with gonadotropin-releasing hormone (GnRH) agonists showed to be effective in a few cases. We present a case of 29-years-old women who has aggressive angiomyxoma which was misdiagnosed as bartholin duct cyst. She was treated by wide local excision with postoperative adjuvant GnRH agonist therapy for 3 months. She is now free of disease during 9 months of follow up. We have described this case with the brief of literature.