Korean J Obstet Gynecol.  2007 Jan;50(1):111-116.

Spontaneous regression of the mild cervical dysplasia and its related factors

• Cho YS
• Jung HJ
• Jeon SR
• Cho HJ
• Son GH
• Choi EK

Abstract

OBJECTIVE
The aim of this study was to assess the regression rate of the mild cervical dysplasia and to examine the factors associated with the regression.
METHODS
One hundred and nine women pathologically confirmed with mild cervical dysplasia were recruited into this study. They were followed up by cytology, colposcopy and human papillomavirus DNA test at 3 months and 6 months after the diagnosis. The participants filled out a questionnaire on their demographic characteristics and sexual history.
RESULTS
The rate of spontaneous regression for the mild cervical dysplasia was 59.6%(65/109). Multivariate analysis showed that initial ASCUS cytology, negative HPV status, non-smoker, condom user and age under 40 years old were associated with higher regression rate.
CONCLUSIONS
The rate of regression for mild cervical dysplasia seen in our study was particularly higher than the result in previous study. Therefore, we recommend that the patients with mild cervical dysplasia can be followed up by cytology and HPV DNA study without any intervention, especially in young patients. Initial ASCUS cytology, negative HPV status, non-smoker, condom user and age under 40 years old were good related factors for regression.

Keyword

Regression; Mild cervical dysplasia; Related factors

MeSH Terms

Adult
Colposcopy
Condoms
Diagnosis
DNA
Female
Humans
Multivariate Analysis
Surveys and Questionnaire
DNA