Korean J Obstet Gynecol.
2007 Jan;50(1):16-27.
Twin-twin transfusion syndrome; TTTS
- Affiliations
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- 1Department of Obstetrics and Gynecology Ajou University School of Medicine, Suwon, Korea. kimhs7@ajou.ac.kr
Abstract
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Twin-twin transfusion syndrome (TTTS) is a complex cardiovascular disease affecting monochorionic (MC) twin pregnancies, and has a high perinatal mortality rate. Its pathogenesis remains poorly understood, but TTTS involves unbalanced transfusion of blood from a donor to a recipient along one or more placental arteriovenous anastomosis in absence of adequate compensatory superficial counter-transfusion. Recent data demonstrated laser ablation to be better than amnioreduction, especially when the condition develops before 26 weeks of gestation.