Korean J Obstet Gynecol.  2004 Nov;47(11):2217-2223.

Three cases of Twin-to-Twin Transfusion Syndrome which were managed with maternal digitalization

Affiliations
  • 1Department of Obstetrics and Gynecology, Dong-A University, College of Medicine, Busan, Korea.
  • 2Department of Pediatrics, Dong-A University, College of Medicine, Busan, Korea.

Abstract

Twin-to-twin transfusion syndrome (TTTS) is one of the complications showing high mortality rate in monochorionic twins with vascular communication in the placenta. Clinical manifestations of TTTS are usually characterized by polyhydramnios, circulatory overload, cardiac failure and fetal hydrops in the recipient twin and symmetrical fetal growth restriction, oligohydramnios, hypovolemia and anemia in the donor twin. TTTS occurres in 10-35% of monochorionic twins. We report three cases of TTTS with fetal hydrops in which amnioreduction was serially attempted and maternal digoxin treatment was tried for the therapeutic purpose.

Keyword

Twin-to-twin transfusion syndrome (TTTS); Amnioreduction; Digoxin; Fetal therapy

MeSH Terms

Anemia
Digoxin
Female
Fetal Development
Fetal Therapies
Fetofetal Transfusion*
Heart Failure
Humans
Hydrops Fetalis
Hypovolemia
Mortality
Oligohydramnios
Placenta
Polyhydramnios
Pregnancy
Tissue Donors
Digoxin
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