Korean J Obstet Gynecol.  2006 Jul;49(7):1578-1583.

A Case of Ovarian Malignant Melanoma showing Peritoneal Dissemination with Unknown Primary Origin

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, Kyung Hee University, Seoul, Korea. diners99@yahoo.co.kr
  • 2Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea.
  • 3Department of Radiology, College of Medicine, Kyung Hee University, Seoul, Korea.

Abstract

Malignant melanoma is a neoplasm of the skin and mucous membrane which very rarely occurs in the ovary. Malignant melanomas occurring in the ovary must be differentiated from primary and metastatic malignant melanoma. Primary malignant melanoma of the ovary is extremely rare and is thought to originate from a cystic teratoma. Malignant melanoma of ovary without evidence of residual teratoma must be considered metastatic even in the absence of a previously cutaneous or mucocutaneous lesion. Opinions about its histogenesis, diagnostic criteria and elective treatment are controversial because of rare manifestations, and the prognosis remains poor in spite of the variety of therapeutic measures. After thoroughly surveying the specific literature, we report case of malignant melanoma with multiple metastases located in the stomach, the omentum and both ovaries with unknown site of primary origin.

Keyword

Malignant melanoma; Peritoneal dissemination; Unknown origin; Ovary

MeSH Terms

Female
Melanoma*
Mucous Membrane
Neoplasm Metastasis
Omentum
Ovary
Prognosis
Skin
Stomach
Teratoma
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