Korean J Obstet Gynecol.  2004 May;47(5):988-991.

A Case of Edward Syndrome with Choroid Plexus Cyst

Affiliations
  • 1Grace Women's Hospital, Korea.

Abstract

Trisomy 18 is the second most common chromosomal anomaly which reach to live birth next to Down syndrome. Several methods were proposed to screen patients on the risk of Edward syndrome like maternal serum levels of total human chorionic gonadotropin (hCG), alpha-fetoprotein (AFP) and unconjugated estriol or free beta hCG with AFP, but the serum screening has only 67% detection rate with a 7.2% of false positive rate. Therefore, in order to overcome the limitations which the serum markers have, detailed ultrasound examination is also necessary and sensitivity of 80% was reported. We report a case of Trisomy 18 fetus in which choroid plexus cyst was the only abnormal sonographic finding.

Keyword

Edward syndrome; Choroid plexus cyst

MeSH Terms

alpha-Fetoproteins
Biomarkers
Chorionic Gonadotropin
Choroid Plexus*
Choroid*
Down Syndrome
Estriol
Fetus
Humans
Live Birth
Mass Screening
Trisomy
Ultrasonography
Chorionic Gonadotropin
Estriol
alpha-Fetoproteins
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