Korean J Obstet Gynecol.  2004 Jan;47(1):178-182.

A Case of Placental Site Trophoblastic Tumor

• Kim JH
• Chang KH
• Ahn ST
• Joo HJ
• Lee JP
• Ryu HS

Abstract

Placntal site trophoblastic tumor (PSTT) has been demonstrated to be a rare form of gestational trophoblastic tumor (GTT). Kurman (1976) et al recognized this disease as Trophoblastic pseudotumor and they thought it to be a benign exaggerated placental site reaction, but Twiggs et al (1981) reported a patient who died of widespread metastasis. Death has been reported in 2 of 14 cases due to metastatic disease, and therefore it is thought to have a malignant course and metastatic potential. It may occur at any age during the reproductive age but usually occurs in relation to second or subsequent pregnancies (a normal pregnancy, an abortion, or a molar pregnancy) rather than primipara. PSTT can metastasis to the brain, lung, liver, vagina and bladder. Larsen et al (1991) report metastasis rate about 10%. It produces little hCG and larger quantities of hPL. We experienced a case of PSTT after normal delivery, which was diagnosed and operated on in our hospital, and report this case with a brief review of literatures.

Keyword

Placental site trophoblastic tumor

MeSH Terms

Brain
Humans
Liver
Lung
Molar
Neoplasm Metastasis
Pregnancy
Trophoblastic Neoplasms
Trophoblastic Tumor, Placental Site*
Trophoblasts
Urinary Bladder
Vagina