Korean J Obstet Gynecol.  2003 Jul;46(7):1358-1362.

The Comparative Analysis of Cytology, Colposcopically Directed Biopsy and Final Histopathology in Diagnosis of Cervical Neoplasia

• Kim HR
• Kim HH
• Chun YY
• Gu JY
• Hong SW
• Sun JG
• Kee KS

Abstract

OBJECTIVE
To investigate the necessity of colposcopically directed biopsy for more accurate detection of cervical neoplasm.
METHODS
Cytology and colposcopically directed biopsy were performed in 114 patients and the patients were subsequently underwent conization or hysterectomy from January, 1998 to December, 2001.
RESULTS
The complete diagnostic agreement of cytology with permanent biopsy was 57.9% (66 of 114) and the diagnostic agreement within one degree was 80.6% (92 of 114). The complete diagnostic agreement of colposcopically directed biopsy with permanent biopsy was 62.3% (71 of 114) and the diagnostic agreement within one degree was 85.1% (97 of 114). The difference between two tests was statistically significant (p<0.001).
CONCLUSION
We concluded that colposcopically directed biopsy can reduce the false negative rate of cytology for screening test of cervical neoplasm. The difference between colposcopically directed biopsy and permanent biopsy was caused by inappropriate resection of the lesion and unskilled physician.

Keyword

Cytology; Colposcopically directed biopsy; Cervical neoplasia

MeSH Terms

Biopsy*
Conization
Diagnosis*
Humans
Hysterectomy
Mass Screening
Uterine Cervical Neoplasms