Korean J Obstet Gynecol.
2003 Apr;46(4):838-841.
A Case of Vulvar Glassy Cell Carcinoma
- Affiliations
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- 1Department of Obstetrics and Gynecology, Dong-A University College of Medicine, Busan, Korea.
- 2Department of Pathology, Dong-A University College of Medicine, Busan, Korea.
Abstract
- Vulvar glassy cell carcinoma (GCC) is a very rare neoplasm. Although GCC is considered to be a poorly differentiated variant of adenosquamous carcinoma, its real nature is still debatable. We report a case of GCC of the vulva in a 53-year-old woman and review the literatures. The patient had bleeding from the lesion of the vulva and pelvic MRI revealed left inguinal lymph node enlargement. Histologically a cytoplasm of ground glass appearance was observed with a distinct cell wall and large nucleus containing prominent nucleoli. The clinical stage of the tumor was III as classified by the International Federation of Gynecology and Obstetrics (FIGO). She was treated by a left hemivulvectomy and bilateral inguinal lymphadenectomy and followed by external irradiation to the pelvis and left inguinal area. The patient was still alive without evidence of disease after 12 months treatment.
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