Korean J Obes.  2012 Mar;21(1):11-17.

The Relationship Between Serum Magnesium Levels and Metabolic Syndrome in Korean Adults

• Song IJ
• Park CH
• Uh WC
• Yang JY
• Lee J
• Lee SH
• Ga H

Abstract

BACKGROUND
Metabolic syndrome is a risk factor of cardiovascular diseases. Previous studies have reported that low serum magnesium levels are related to high blood pressure, diabetes mellitus and dyslipidemia. However, there have been few studies on association between serum magnesium levels and metabolic syndrome. Therefore, we investigated the relationship between them in this study.
METHODS
This study was a cross sectional study including 524 Korean adults who visited a health promotion center in a university hospital from January 2010 to May 2011. Metabolic syndrome was defined according to the criteria of the American Heart Association. Multiple logistic regression analysis was used to evaluate the association between serum magnesium levels and metabolic syndrome, according to the lowest serum magnesium level group (1.8~2.0 mg/dL), the intermediate serum magnesium level group (2.1~2.2 mg/dL) and the highest serum magnesium level group (2.3~2.8 mg/dL).
RESULTS
Compared with the highest serum magnesium level group, the odds ratio for metabolic syndrome in the lowest serum magnesium level group was 3.78 (95% CI = 1.48-9.69), and in the intermediate serum magnesium level group was 1.53 (95% CI = 0.63-3.70). Among the components of metabolic syndrome, the odds ratios for abdominal obesity and hyperglycemia in the lowest serum magnesium level group were 5.48 (95% CI = 2.07-14.47), 2.41 (95% CI = 0.98~5.89) and for intermediate serum magnesium level group were 3.12 (95% CI = 1.25~7.78), 0.99 (95% CI = 0.40~2.43), respectively.
CONCLUSIONS
A significant association was found between low serum magnesium levels and metabolic syndrome in Korean adults.

Keyword

Magnesium; Metabolic syndrome; Obesity; Diabetes mellitus; Hypertension; Dyslipidemia

MeSH Terms

Adult
American Heart Association
Cardiovascular Diseases
Diabetes Mellitus
Dyslipidemias
Health Promotion
Humans
Hyperglycemia
Hypertension
Logistic Models
Magnesium
Obesity
Obesity, Abdominal
Odds Ratio
Risk Factors
Magnesium