Asian Spine J.  2014 Oct;8(5):581-590. 10.4184/asj.2014.8.5.581.

Magnetic Resonance Imaging Evaluation of L5-S1 Intervertebral Disc Degeneration in Japanese Women

• Hagiwara H
• Shibata H
• Sakakibara H
• Inoue T

• KMID: 2270239
• DOI: http://doi.org/10.4184/asj.2014.8.5.581

Abstract

STUDY DESIGN: Retrospective case series. PURPOSE: To calculate the prevalence of L5-S1 intervertebral disc degeneration (IDD) by evaluating gynecological disease findings, obtained by pelvic magnetic resonance imaging (MRI), and reveal the risk factors for IDD by analyzing its relationship with age, sacral structure, body mass index (BMI), number of deliveries, and intrapelvic space-occupying lesions. OVERVIEW OF LITERATURE: Age, obesity, height, smoking history, occupation, and lumbosacral structure are reportedly the main factors of lumbar IDD. However, in women, the relationship of IDD with obstetric and gynecological history is unclear.
METHODS
The presence of L5-S1 IDD was evaluated on sagittal T2-weighted pelvic MRI during gynecological evaluations in 660 Japanese women. We measured the sacral table angle (STA), sacral kyphosis angle (SKA), and intrapelvic space-occupying lesion size. Age, height, weight, BMI, number of deliveries, lumbosacral structure, size of space-occupying lesions, and presence of uterine leiomyoma based on medical records were compared between the IDD-positive and IDD-negative groups.
RESULTS
Lumbosacral IDD was observed in 405 cases (61.4%), and its prevalence increased with age. Differences in age, height, weight, BMI, and number of deliveries between the IDD-positive and -negative groups were significant, but differences in STA, SKA, and presence of uterine leiomyoma and space-occupying lesion size were not. Logistic regression analysis indicated that age, BMI, and STA were risk factors for lumbosacral IDD.
CONCLUSIONS
Age is the biggest risk factor for lumbosacral IDD in Japanese women, with BMI and STA also contributing to its development. However, SKA and obstetric and gynecological history were not significantly involved.

Keyword

Intervertebral disc degeneration; Magnetic resonance imaging; Lumbosalral region; Body mass index; Reproductive history

MeSH Terms

Asian Continental Ancestry Group*
Body Mass Index
Female
Humans
Intervertebral Disc Degeneration*
Kyphosis
Leiomyoma
Logistic Models
Magnetic Resonance Imaging*
Medical Records
Obesity
Occupations
Prevalence
Reproductive History
Retrospective Studies
Risk Factors
Smoke
Smoking
Smoke