Korean J Med.  2014 May;86(5):627-631.

A Case of Infective Endocarditis with Cytomegalovirus Infection after Kidney Transplantation

Affiliations
  • 1Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. sh76so@cau.ac.kr
  • 2Department of Thoracic and Cardiovascular Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Chung-Ang University College of Medicine, Seoul, Korea.

Abstract

Advances in immunosuppressive therapy have increased the survival of kidney transplant recipients, yet suppression of the immune system after transplantation can promote infectious complications. Cytomegalovirus (CMV) infection remains one of the most important complications following kidney transplantation and it is a risk factor for developing superinfections with other organisms. Aspergillus endocarditis is a rare life-threatening complication in kidney transplantation. Coinfection of CMV and Aspergillus endocarditis is rare worldwide and has not been reported in Korea. We report a case of Aspergillus endocarditis that developed in a patient with CMV infection after kidney transplantation. His clinical condition did not improve despite mitral valve replacement and empirical antibiotic treatment, but he was eventually treated successfully with antifungal agents for 6 weeks.

Keyword

Aspergillus; Cytomegalovirus; Endocarditis; Kidney transplantation

MeSH Terms

Antifungal Agents
Aspergillus
Coinfection
Cytomegalovirus
Cytomegalovirus Infections*
Endocarditis*
Humans
Immune System
Kidney
Kidney Transplantation*
Korea
Mitral Valve
Risk Factors
Superinfection
Transplantation
Antifungal Agents
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