Korean J Med.  2014 Sep;87(3):373-378. 10.3904/kjm.2014.87.3.373.

A Case of Peripheral Bone Tuberculosis Mimicking Rheumatoid Arthritis

Affiliations
  • 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. sungyk@hanyang.ac.kr
  • 2Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University Collee of Medicine, Goyang, Korea.
  • 3Department of Radiology, Hanyang University College of Medicine, Seoul, Korea.
  • 4Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.

Abstract

A 30 year-old female visited our out-patient clinic with painful joint swelling in both hands and feet. Because she had tested positive for rheumatoid factor, and her inflammatory markers were elevated, the case was initially classified as rheumatoid arthritis (RA), according to the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria. However, radiographic examinations, including simple radiography and MRI, revealed that her peripheral bone lesions were compatible with bone tuberculosis. The patient also exhibited pulmonary tuberculosis (TB) on chest X-ray and CT examinations. She was treated with isoniazid (INH), rifampicin (RFP), ethambutol (EMB), and pyrazinamide (PZA), and exhibited a good response to these medications. The patient was diagnosed as having bone TB, and her peripheral bone lesions were resolved using anti-TB treatment. This was an uncommon case of bone TB mimicking RA.

Keyword

Tuberculosis; Rheumatoid arthritis

MeSH Terms

Arthritis, Rheumatoid*
Classification
Ethambutol
Female
Foot
Hand
Humans
Isoniazid
Joints
Magnetic Resonance Imaging
Outpatients
Pyrazinamide
Radiography
Rheumatic Diseases
Rheumatoid Factor
Rheumatology
Rifampin
Thorax
Tuberculosis
Tuberculosis, Osteoarticular*
Tuberculosis, Pulmonary
Ethambutol
Isoniazid
Pyrazinamide
Rheumatoid Factor
Rifampin
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