Korean J Med.
2013 May;84(5):755-758.
Pericardial Amyloidosis Associated with Light-chain Myeloma
- Affiliations
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- 1Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea. leehr@paik.ac.kr
- 2Department of Pathology, Inje University Ilsan Paik Hospital, Goyang, Korea.
Abstract
- Amyloidosis is characterized by the deposition of amyloid fibrils, which cause both functional and structural damage to organs. Cardiac involvement with amyloids is a common cause of secondary cardiomyopathy and leads to congestive heart failure. Pericardial amyloidosis usually occurs at the late or terminal stage of the disease after myocardial involvement, but it is extremely rare for pericardial amyloidosis to proceed with myocardial involvement. Here, we report a rare case of a 66-year-old patient with light-chain myeloma, who presented with pericardial effusion but no evidence of cardiomyopathy.