Ann Surg Treat Res.  2015 Mar;88(3):166-169. 10.4174/astr.2015.88.3.166.

An idiopathic gigantomastia

• Cho MJ
• Yang JH
• Choi HG
• Kim WS
• Yu YB
• Park KS

• KMID: 2266875
• DOI: http://doi.org/10.4174/astr.2015.88.3.166

Abstract

Gigantomastia is a rare condition characterized by excessive breast growth. It has been reported that the majority of gigantomastia cases occur during either pregnancy or puberty. We were presented with a rare case of gigantomastia associated with neither pregnancy nor puberty, and successfully treated it with reduction mammaplasty and free nipple graft. This idiopathic gigantomastia is the very first case in Korea, and adds to the worldwide total of 9 reported cases.

Keyword

Gigantomastia; Breast; Reduction; Mammaplasty

MeSH Terms

Adolescent
Breast
Female
Humans
Korea
Mammaplasty
Nipples
Pregnancy
Puberty
Transplants

Figure

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  Fig. 1 Gigantomastia in a 43-year-old woman. Patient before reduction mammaplasty: (A) frontal and (B) lateral view.

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  Fig. 2 Two-months postoperative results.

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  Fig. 3 The histology shows a nodular, compact proliferation of small round tubules lined by epithelial and myoepithelial cells (H&E, ×400).

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  Fig. 4 Immunohistochemistry staining: (A) the epithelial cells show 10% estrogen receptor positivity with intermediate intensity (magnification, (×400)); (B) the epithelial cells show 10% progesterone receptor positivity with intermediate intensity (magnification, (×400)).

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