Ann Rehabil Med.  2012 Aug;36(4):544-550. 10.5535/arm.2012.36.4.544.

The Predictive Value of SigmaDeltaST/DeltaHR Index for Restenosis after Percutaneous Coronary Intervention

• Kim C
• Choi HE

• KMID: 2266726
• DOI: http://doi.org/10.5535/arm.2012.36.4.544

Abstract

OBJECTIVE
To find out the predictive value of the SigmaDeltaST/DeltaHR index for restenosis after percutaneous coronary intervention (PCI). METHOD: Subjects of this research were patients who participated in a cardiac rehabilitation (CR) program as six to eight weeks of a hospital-based program after receiving PCI to treat acute coronary syndrome (ACS). The patients received coronary angiography (CAG) at the onset of the ACS and nine months after that, and also received an exercise tolerance test (ETT) at the start of the CR program and several days before receiving a follow-up CAG. In ETT, we used the sum of the ST depression (SigmaDeltaST index) of leads II, III, aVF, V4-6 as well as the sum of the DeltaST/DeltaHR (heart rate) (SigmaDeltaST/DeltaHR index) in the same leads and the sum of the DeltaST/DeltaRPP (rate pressure product) (SigmaDeltaST/DeltaRPP index) in the same leads. We compared the predictive power of each index of ETT for restenosis after PCI.
RESULTS
The sensitivity, specificity, positive predictive value, and negative predictive value of SigmaDeltaST index were 69%, 47%, 31%, and 82%. The SigmaDeltaST/DeltaHR index was 13.7+/-5.2 in the restenosis group and 9.3+/-5.6 in the patent group (p=0.017). The sensitivity, specificity, positive predictive value, and negative predictive value of this index were 85%, 63%, 44%, and 92%. The SigmaDeltaST/DeltaRPP index were 0.10+/-0.08 in the restenosis group and 0.06+/-0.04 in the patent group (p=0.016). The sensitivity, specificity, positive predictive value, and negative predictive value of this index were 54%, 76%, 44%, and 83%.
CONCLUSION
The SigmaDeltaST/DeltaHR index showed a much higher sensitivity and negative predictive value for restenosis after PCI compared to the SigmaDeltaST index.

Keyword

Coronary artery disease; Rehabilitation; Exercise test; Coronary restenosis

MeSH Terms

Acute Coronary Syndrome
Coronary Angiography
Coronary Artery Disease
Coronary Restenosis
Depression
Exercise Test
Exercise Tolerance
Follow-Up Studies
Humans
Percutaneous Coronary Intervention
Sensitivity and Specificity

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